SALOR-INT L317853-1EA

SALOR-INT L317853-1EA - Names and Identifiers

Name	3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE
Synonyms	BUTTPARK 303-80 SALOR-INT L317853-1EA 5-AMINO-3-(4-CHLOROPHENYL)PYRAZOLE 3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE 5-(4-Chlorophenyl)-1H-pyrazol-3-amine 3-Amino-5-(4-chlorophenyl)-1H-pyrazole 5-(4-CHLOROPHENYL)-2H-PYRAZOL-3-YLAMINE
CAS	78583-81-0

SALOR-INT L317853-1EA - Physico-chemical Properties

Molecular Formula	C9H8ClN3
Molar Mass	193.63
Melting Point	172-176°C(lit.)
Storage Condition	Room Temprature

SALOR-INT L317853-1EA - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R37/38 - Irritating to respiratory system and skin. R41 - Risk of serious damage to eyes
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
Hazard Class	IRRITANT

SALOR-INT L317853-1EA - Upstream Downstream Industry

Raw Materials

2-Propenenitrile, 2-chloro-3-(4-chlorophenyl)-
ETHYL 4-CHLOROBENZOATE
3-CHLORO-3-(4-CHLOROPHENYL)ACRYLONITRILE
4-CHLOROBENZOYLACETONITRILE
METHYL 4-CHLOROBENZOATE
4-Chlorobenzoic acid

SALOR-INT L317853-1EA - Introduction

3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE is an organic compound containing an amino group and a pyrazole ring, as well as a chloro-substituted benzene ring in its chemical structure. The following is a detailed description of its nature, use, formulation and safety information:

Nature:
-Appearance: colorless or light yellow crystal
-Molecular formula: C9H8ClN3
-Molecular Weight: 195.63
-Melting point: 129-131 ° C
-Solubility: Soluble in most organic solvents such as alcohols and esters, insoluble in water

Use:
3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE has important applications in the field of medicine:
-Anticancer drug research: It is used as a potential anti-tumor compound for cancer treatment related research.
-Anti-inflammatory drug research: It is also used in a new field of research and development of anti-inflammatory drugs.

Method:
A common preparation method is as follows:
1. First, 4-chlorobenzoic acid reacts with sodium nitrite under acidic conditions to generate the corresponding amino compound.
2. Then, the above product is condensed with 1H-pyrazole-5-carboxylic acid chloride under basic conditions.
3. Finally, the salt obtained by the reaction is formed into pyrazolamine by acid treatment.

Safety Information:
- 3-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE is generally considered to be relatively safe under regular use.
-However, it is still an organic compound and needs to be handled and stored carefully to avoid contact with skin and eyes.
-Follow appropriate chemical laboratory practices and personal protective measures at the time of use.
-If the compound is inhaled or ingested, seek medical attention immediately.

Last Update：2024-04-09 21:01:54